2025

Peripheral blood CD4+ and CD8+ T cell responses to Cryptococcus candidate vaccine antigens in human subjects with and without cryptococcosis.

Oliveira LVN, Hargarten JC, Wang R, Carlson D, Park YD, Specht CA, Williamson PR, Levitz SM. Journal of Infection. 2025. 91(1):106521. doi: 10.1016/j.jinf.2025.106521. PMID: 40449806.

Pathway-instructed therapeutic selection of ruxolitinib reduces neuroinflammation in fungal postinfectious inflammatory syndrome.

Hargarten JC, Ssebambulidde K, Anjum SH, Vaughan MJ, Xu J, Ganguly A, Dulek B, Otaizo-Carrasquero F, Song B, Tao S, Park YD, Scott TL, Höltermann TA, Schinazi RF, Chittiboina P, Billioux BJ, Hammoud DA, Olszewski MA, Williamson PR. Science Advances. 2025. 11(12):eadi9885. doi: 10.1126/sciadv.adi9885. PMID: 40117367; PMCID: PMC11927619.

2023

Tocilizumab as a Potential Adjunctive Therapy to Corticosteroids in Cryptococcal Post-infectious Inflammatory Response Syndrome (PIIRS): a Report of Two Cases.

Hargarten JC, Anjum SH, Ssebambulidde K, Park YD, Vaughan MJ, Scott TL, Hammoud DA, Billioux BJ, Williamson PR. Journal of Clinical Immunology. 2023. 43(8):2146-2155. doi: 10.1007/s10875-023-01592-7. PMID: 37814084.

Persistent neurological symptoms and elevated intracranial pressures in a previously healthy host with cryptococcal meningitis.

El-Atoum M, Hargarten JC, Park YD, Ssebambulidde K, Ding L, Chittiboina P, Hammoud DA, Anjum SH, Glassman SR, Merchant S, Williamson PR, Hu JC. BMC Infectious Diseases. 2023. 23(1):407. doi: 10.1186/s12879-023-08349-y. PMID: 37316806; PMCID: PMC10265895.

Farnesol remodels the peritoneal cavity immune environment influencing Candida albicans pathogenesis during intra-abdominal infection.

Hargarten JC, Vaughan MJ, Lampe AT, Jones RM, Ssebambulidde K, Nickerson KW, Williamson PR, Atkin AL, Brown DM. Infection & Immunity. 2023. 91(12):e0038423. doi: 10.1128/iai.00384-23. PMID: 37975682; PMCID: PMC10715096.

Measurement of SQSTM1 by flow cytometry.

Hargarten JC, Hu G, Elsegeiny W, Williamson PR. Autophagy. 2023. (10):2789-2799. doi: 10.1080/15548627.2023.2224074. PMID: 37335017; PMCID: PMC10472860.

2022

Treatment recommendations for non-HIV associated cryptococcal meningoencephalitis including management of post-infectious inflammatory response syndrome.

Ssebambulidde K, Anjum SH, Hargarten JC, Chittiboina P, Shoham S, Seyedmousavi S, Marr KA, Hammoud DA, Billioux BJ, Williamson PR. Frontiers in Neurology. 2022. 13:994396. doi: 10.3389/fneur.2022.994396. PMID: 36530631; PMCID: PMC9751747.

2020

Chemokine receptor CXCR3 is required for lethal brain pathology but not pathogen clearance during cryptococcal meningoencephalitis.

Xu J, Neal LM, Ganguly A, Kolbe JL, Hargarten JC, Elsegeiny W, Hollingsworth C, He X, Ivey M, Lopez R, Zhao J, Segal B, Williamson PR, Olszewski MA. Science Advances. 2020. 6(25):eaba2502. doi: 10.1126/sciadv.aba2502. PMID: 32596454; PMCID: PMC7299622.

2018

Epigenetic Regulation of Autophagy: A Path to the Control of Autoimmunity.

Hargarten JC, Williamson PR. Frontiers in Immunology. 2018. 9:1864. doi: 10.3389/fimmu.2018.01864. PMID: 30154791; PMCID: PMC6102341.

2015

Candida albicans Quorum Sensing Molecules Stimulate Mouse Macrophage Migration.

Hargarten JC, Moore TC, Petro TM, Nickerson KW, Atkin AL. Infection & Immunity. 2015. 83(10):3857-64. doi: 10.1128/IAI.00886-15. PMID: 26195556; PMCID: PMC4567634.